More than 125 million Americans have at least one chronic health condition, and 60 million have more than one. These people, many of them elderly, manage multiple conditions, treatments, medications, and doctors. Primary care doctors often don’t have the time or resources to properly manage these complex, chronic health problems. So these patients and the family members who care for them are often less healthy, confused by their treatments and medications, and overwhelmed by high health care costs. As the baby boomers age, this problem will multiply. In response, a multidisciplinary team of experts from the Lipitz Center for Integrated Health Care at the Johns Hopkins Bloomberg School of Public Health designed Guided Care as a model of comprehensive health care by physician-nurse teams for people with several chronic health conditions, specifically focusing on the 25% of Medicare patients at highest risk for using health services heavily.